Regaine for Men Extra Strength Scalp Foam 5 Percent w/w Cutaneous Foam Minoxidil , 3 Month's Supply Easy to Ese Foam, 73 ml (Pack of 3)

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Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding. Drug Interactions There aren’t many studies that have investigated the use of Minoxidil for beard growth , so it’s unclear whether Minoxidil foam or liquid is best for treating beard hair loss .

There is some evidence from in vitro studies that minoxidil reversibly binds to human plasma proteins. However, since only 1 – 2% of topically applied minoxidil is absorbed, the extent of plasma protein binding occurring in vivo after topical application would be clinically insignificant. The volume of distribution of minoxidil after intravenous administration has been estimated at 70 litres. There is some evidence from in vitro studies that minoxidil reversibly binds to human plasma proteins. However, since only 1 – 2% of topically applied minoxidil is absorbed, the extent of plasma protein binding occurring in vivo after topical application would be clinically insignificant. The volume of distribution of minoxidil doses between 1.37 mg and 27.4 mg at steady state after 12-hour intravenous administration ranges from 76.0 to 82.8, respectively. The solution comes in a small bottle with a pump. Use the pump to apply 1ml of the solution to your scalp each morning and night. Regaine for Men Extra Strength Scalp Solution 5% w/v Cutaneous Solution is indicated for the treatment of alopecia androgenetica in men. It is important to speak to your doctor before you start using Minoxidil. This is because over-the-counter minoxidil such as Regaine is only licensed for use on hereditary hair loss (male and female pattern baldness). If you are experiencing hair loss of another kind, then treatment with minoxidil may not be suitable. Hair loss treatment with Online DoctorYour hair growth should start to improve within 2-3 months, although it can take up to a year for you to notice the full benefit. The new hair may be fine and downy to begin with, but this should improve. Make sure your hair and scalp are dry before you apply minoxidil. It is recommended that you leave about an hour between washing your hair and applying the preparation. A multicenter, randomized, placebo-controlled, double-blind clinical trial of a novel formulation of 5% minoxidil topical foam versus placebo in the treatment of androgenetic alopecia in men

The 5% minoxidil foam group showed a better score in the expert panel review (EPR) than the placebo foam group (adjusted mean 0.5 vs 0.1, p<0.0001). Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. The exact mechanism of action of minoxidil for topical treatment of alopecia is not fully understood, but minoxidil can reverse the hair loss process of androgenetic alopecia by the following means: Some consumers reported increased hair shedding upon initiation of therapy with this product. This is most likely due to minoxidil's action of shifting hairs from the resting telogen phase to the growing anagen phase (old hairs fall out as new hairs grow in their place). This temporary increase in hair shedding generally occurs two to six weeks after beginning treatment and subsides within a couple of weeks. If shedding persists (> 2 weeks), users should stop using this product and consult their doctor.Topical minoxidil (5% foam, 5% solution, and 2% solution) is FDA-approved for androgenetic alopecia (AGA) in men and women. Mechanism of action: Minoxidil acts through multiple pathways (vasodilator, anti-inflammatory agent, inducer of the Wnt/β-catenin signaling pathway, an antiandrogen), and may also affect the length of the anagen and telogen phases. Pharmacokinetics: Approximately 1.4% of topical minoxidil is absorbed through the skin. Minoxidil is a prodrug that is metabolized by follicular sulfotransferase to minoxidil sulfate (active form). Those with higher sulfotransferase activity may respond better than patients with lower sulfotransferase activity. Clinical efficacy (topical minoxidil): In a five-year study, 2% minoxidil exhibited peak hair growth in males at year one with a decline in subsequent years. Topical minoxidil causes hair regrowth in both frontotemporal and vertex areas. The 5% solution and foam were not significantly different in efficacy from the 2% solution. Oral and Sublingual minoxidil (not FDA approved; off-label): After 6 months of administration, minoxidil 5 mg/day was significantly more effective than topical 5% and 2% in male AGA. Low-dose 0.5-5 mg/day may also be safe and effective for female pattern hair loss and chronic telogen effluvium. Sublingual minoxidil may be safe and effective in male and female pattern hair loss.

This medicine usually comes with patient instructions. It is important that you read the instructions carefully.As with any medicine, Minoxidil comes with some mild side effects such as mild skin irritations. However if you experience any side effects you should stop using Regaine and tell your doctor or pharmacist.