Zebra F Refill Ballpoint Pen for F-301, F-701, Expandz & Spiral. Pack of 12 Black

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Teixidó E, Kießling TR, Krupp E, Quevedo C, Muriana A, Scholz S (February 2019). "Automated Morphological Feature Assessment for Zebrafish Embryo Developmental Toxicity Screens". Toxicological Sciences. 167 (2): 438–449. doi: 10.1093/toxsci/kfy250. PMC 6358258. PMID 30295906.

a b c White RM, Sessa A, Burke C, Bowman T, LeBlanc J, Ceol C, etal. (February 2008). "Transparent adult zebrafish as a tool for in vivo transplantation analysis". Cell Stem Cell. 2 (2): 183–189. doi: 10.1016/j.stem.2007.11.002. PMC 2292119. PMID 18371439. Plains zebra subspecies include the maneless zebra, grant’s zebra, crawshay’s zebra, chapman’s zebra, burchell’s zebra, and selous’ zebra, which have different geographical distributions. Kimmel CB, Law RD (March 1985). "Cell lineage of zebrafish blastomeres. III. Clonal analyses of the blastula and gastrula stages". Developmental Biology. 108 (1): 94–101. doi: 10.1016/0012-1606(85)90012-0. PMID 3972184. McCluskey BM, Postlethwait JH (March 2015). "Phylogeny of zebrafish, a "model species", within Danio, a "model genus" ". Molecular Biology and Evolution. 32 (3): 635–652. doi: 10.1093/molbev/msu325. PMC 4327152. PMID 25415969.ZMotif SDK and programming documentation (job command information, coding sequence and sample code) and DLL libraries for: Multiple family groups come together to form herds. Often as herds are migrating, they form ‘super herds’ with thousands of zebras. Other herd animals join in too, such as wildebeest and antelope.

Gerhard GS, Kauffman EJ, Wang X, Stewart R, Moore JL, Kasales CJ, etal. (2002). "Life spans and senescent phenotypes in two strains of Zebrafish ( Danio rerio)". Experimental Gerontology. 37 (8–9): 1055–1068. doi: 10.1016/s0531-5565(02)00088-8. PMID 12213556. S2CID 25092240. Various transgenic and mutant strains of zebrafish were stored at the China Zebrafish Resource Center (CZRC), a non-profit organization, which was jointly supported by the Ministry of Science and Technology of China and the Chinese Academy of Sciences. [ citation needed] Wild-type strains [ edit ] The zebrafish is named for the five uniform, pigmented, horizontal, blue stripes on the side of the body, which are reminiscent of a zebra's stripes, and which extend to the end of the caudal fin. Its shape is fusiform and laterally compressed, with its mouth directed upwards. The male is torpedo-shaped, with gold stripes between the blue stripes; the female has a larger, whitish belly and silver stripes instead of gold. Adult females exhibit a small genital papilla in front of the anal fin origin. The zebrafish can reach up to 4–5cm (1.6–2.0in) in length, [12] although they typically are 1.8–3.7cm (0.7–1.5in) in the wild with some variations depending on location. [9] Its lifespan in captivity is around two to three years, although in ideal conditions, this may be extended to over five years. [16] [18] In the wild it is typically an annual species. [1] Psychology [ edit ] a b Broughton RE, Milam JE, Roe BA (November 2001). "The complete sequence of the zebrafish ( Danio rerio) mitochondrial genome and evolutionary patterns in vertebrate mitochondrial DNA". Genome Research. 11 (11): 1958–1967. doi: 10.1101/gr.156801. PMC 311132. PMID 11691861.Levraud JP, Palha N, Langevin C, Boudinot P (September 2014). "Through the looking glass: witnessing host-virus interplay in zebrafish". Trends in Microbiology. 22 (9): 490–497. doi: 10.1016/j.tim.2014.04.014. PMID 24865811. Lawrence JM, Singhal S, Bhatia B, Keegan DJ, Reh TA, Luthert PJ, etal. (August 2007). "MIO-M1 cells and similar muller glial cell lines derived from adult human retina exhibit neural stem cell characteristics". Stem Cells. 25 (8): 2033–2043. doi: 10.1634/stemcells.2006-0724. PMID 17525239.

Zebrafish pancreas development is very homologous to mammals, such as mice. The signaling mechanisms and way the pancreas functions are very similar. The pancreas has an endocrine compartment, which contains a variety of cells. Pancreatic PP cells that produce polypeptides, and β-cells that produce insulin are two examples of those such cells. This structure of the pancreas, along with the glucose homeostasis system, are helpful in studying diseases, such as diabetes, that are related to the pancreas. Models for pancreas function, such as fluorescent staining of proteins, are useful in determining the processes of glucose homeostasis and the development of the pancreas. Glucose tolerance tests have been developed using zebrafish, and can now be used to test for glucose intolerance or diabetes in humans. The function of insulin are also being tested in zebrafish, which will further contribute to human medicine. The majority of work done surrounding knowledge on glucose homeostasis has come from work on zebrafish transferred to humans. [143] Obesity [ edit ] Whiteley, Andrew R.; Bhat, Anuradha; Martins, Emilia P.; Mayden, Richard L.; Arunachalam, M.; Uusi‐Heikkilä, Silva; Ahmed, A. T. A.; Shrestha, Jiwan; Clark, Matthew; Stemple, Derek; Bernatchez, Louis (2011). "Population genomics of wild and laboratory zebrafish ( Danio rerio )". Molecular Ecology. 20 (20): 4259–4276. doi: 10.1111/j.1365-294X.2011.05272.x. PMC 3627301. PMID 21923777. Benard EL, van der Sar AM, Ellett F, Lieschke GJ, Spaink HP, Meijer AH (March 2012). "Infection of zebrafish embryos with intracellular bacterial pathogens". Journal of Visualized Experiments (61). doi: 10.3791/3781. PMC 3415172. PMID 22453760. The most common species is the plains zebra, which roams grasslands and woodland of eastern and southern Africa. The Grevy’s zebra can be found in dry, semi-desert areas of Kenya and Ethiopia, and the mountain zebra lives in mountainous and hilly habitats in Namibia, Angola and South Africa.

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Bradley K, Breyer P, Melville D, Broman K, Knapik E, Smith JR (Jun 2011). "A SNP-Based Linkage Map for Zebrafish Reveals Sex Determination Loci". G3 (Bethesda). 1 (1): 3–9. doi: 10.1534/g3.111.000190. PMC 3178105. PMID 21949597. S2CID 11161125.

There are well-established protocols for editing zebrafish genes using CRISPR-Cas9 [85] and this tool has been used to generate genetically modified models.Stainier DY, Raz E, Lawson ND, Ekker SC, Burdine RD, Eisen JS, etal. (October 2017). "Guidelines for morpholino use in zebrafish". PLOS Genetics. 13 (10): e1007000. doi: 10.1371/journal.pgen.1007000. PMC 5648102. PMID 29049395. When close relatives mate, progeny may exhibit the detrimental effects of inbreeding depression. Inbreeding depression is predominantly caused by the homozygous expression of recessive deleterious alleles. [91] For zebrafish, inbreeding depression might be expected to be more severe in stressful environments, including those caused by anthropogenic pollution. Exposure of zebrafish to environmental stress induced by the chemical clotrimazole, an imidazole fungicide used in agriculture and in veterinary and human medicine, amplified the effects of inbreeding on key reproductive traits. [92] Embryo viability was significantly reduced in inbred exposed fish and there was a tendency for inbred males to sire fewer offspring. a b c d Parichy DM (September 2006). "Evolution of danio pigment pattern development". Heredity. 97 (3): 200–210. doi: 10.1038/sj.hdy.6800867. PMID 16835593. Kawakami K, Takeda H, Kawakami N, Kobayashi M, Matsuda N, Mishina M (July 2004). "A transposon-mediated gene trap approach identifies developmentally regulated genes in zebrafish". Developmental Cell. 7 (1): 133–144. doi: 10.1016/j.devcel.2004.06.005. PMID 15239961. Guttridge N (2012). "Targeted gene modification can rewrite zebrafish DNA". Nature. doi: 10.1038/nature.2012.11463. S2CID 87708919.